Jump to the main content block


Jing-Ru Weng Professor

翁靖如 教授
Jing-Ru Weng,


美國俄亥俄州立大學 博士後研究員(2004–2005)
Postdoctoral Fellow of The Ohio State University (2004–2005)
高雄醫學大學 藥學系 博士後研究員(2003–2004)
Postdoctoral Fellow of Kaohsiung Medical University (2003–2004)
Ph.D.(2003) 高雄醫藥大學
Ph.D.(2003) Kaohsiung Medical University
碩士 (1996–1998)高雄醫學大學 藥學研究所
MS (1996–1998)Kaohsiung Medical University
學士 (1993–1996) 高雄醫學院 藥學系
BS (1993–1996)Kaohsiung Medical University
*中山大學海洋生物技術暨資源學系 教授(2018.02起)
  2016 – 2018 中山大學海洋生物技術暨資源學系副教授
  2013 – 2016 中國醫藥大學生物科技學系教授
  2013 – 2014 中國醫藥大學課務組組長
  2008 – 2013 中國醫藥大學生物科技學系副教授
  2005 – 2008 中國醫藥大學生物科技學系助理教授
Email: jrweng@mail.nsysu.edu.tw

106年11月 8日獲「新進教師獎勵」


研究專長: 藥物開發(Drug discovery)
癌症之訊息傳遞(Signal transduction of cancer)
天然物化學(Natural Products Chemistry)
藥物化學(Medicinal Chemistry)



海洋生物科技暨資源學系大學部開設課程 105
年級 科目名稱 學分數 學期/學年 必/選 授課教師
大四 海洋生物製藥 3 學期 翁靖如

海洋生物科技暨資源學系碩士班開設課程 105
年級 科目名稱 學分數 學期/學年 必/選 授課教師
碩一 分子標靶之天然物開發 2 學期 翁靖如



2018 Travel Award, 2018 The Japanese Society of Medical Oncology Annual Meeting, Japan
2017 Travel Award, 2017 The Japanese Society of Medical Oncology Annual Meeting, Japan
2011 The Best Poster, Tri-Society Head and Neck Oncology meeting, Singapore
2009 – 2010 Teacher of the Year Award, Department of Biological Science and Technology, China Medical University
2008 – 2009 Teacher of the Year Award, Department of Biological Science and Technology, China Medical University
2008 The outstanding original contribution, 8th international conference of anticancer research, Greece
2004 行政院國家科學委員會九十三年度補助博士後赴國外或大陸地區研究



1 US 8,153,680 Alkyl indole-3-carbinol-derived antitumor agents
2 US 7,807,705 Potent indole-3-carbinol-derived antitumor agents



1. Jing-Ru Weng*, Eman M. E. Dokla, Li-Yuan Bai, Ching-Shih Chen, Shih-Jiuan Chiu, and Tzong-Ming Shieh, An AMPK activator; compound 59, induces autophagy and apoptosis in human oral squamous cell carcinoma, Basic and Clinical Pharmacology and Toxicology, 2018, 123, 21-29.
2. Jing-Ru Weng, Chang-Fang Chiu, Jing-Lan Hu, Chia-Hsien Feng, Chiung-Yao Huang, Li-Yuan Bai*, and Jyh-Horng Sheu*, A sterol from soft coral induces apoptosis and autophagy in MCF-7 breast cancer cells, Marine Drugs, 2018, accepted, in press.
3. Liang-Chieh Chen, Hui-Ju Tseng, Chang-Yi Liu, Yun-Yi Huang, Cheng-Chung Yen, Jing-Ru Weng, Yeh-Lin Lu, Wen-Chi Hou, Tony E. Lin, I-Horng Pan, Kuo-Kuei Huang, Wei-Jan Huang* and Kai-Cheng Hsu*, Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation, Frontiers in Pharmacology, 2018, 3, 9, 708.
4. Chen-Wen Chen, Wen-Chan Hsu, Ya-Chen Lu, Jing-Ru Weng, Chia-Hsien Fen*, Determination of parabens using two microextraction methods coupled with capillary liquid chromatography-UV detection, Food Chemistry, 2018, 241, 411-418..
5. Jing-Ru Weng*, Li-Yuan Bai, Horng-Huey Ko, and Yi-Tung Tsai, Cyclocommunol induces apoptosis in human oral squamous cell carcinoma partially through a Mcl-1-dependent mechanism, Phytomedicine, 2018, 39,25-32.
6. Chia-Ju Tsai, Fang-Yi Liao, Jing-Ru Weng, Chia-Hsien Feng*, Tandem derivatization combined with salting-out assisted liquid-liquid microextraction for determination of biothiols in urine by gas chromatography-mass spectrometry, Journal of Chromatography A, 2017, 1524, 29-36.
7. Li-Yuan Bai, Chang-Fang Chiu, Shih-Jiuan Chiu, Po-Chen Chu, and Jing-Ru Weng*, FTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism, Scientific Reports, 2017,75600.
8. Jing-Ru Weng*, Li-Yuan Bai, and Wei-Yu Lin, Identification of a triterpenoid as a novel PPARγ activator derived from Formosan plants, Phytotherapy Research, 2017, 31, 1722-1730.
9. Jing-Ru Weng, Chun-Hung Hua, Chao-Hsien Chen, Su-Hua Huang, Ching-Ying Wang, Ying-Ju Lin, Lei Wan, and Cheng-Wen Lin*, Anti-apoptotic activity of Japanese encephalitis virus NS5 protein in human medulloblastoma cells treated with interferon, Journal of Microbiology, Immunology and infection, 2017, accepted, in press.
10. Nan-Chieh Huang, Wan-Ting Hung, Wei-Lun Tsai, Feng-Yi Lai, You-Sheng Lin, Mei-Sui Huang, Jih-Jung Chen, Wei-Yu Lin, Jing-Ru Weng* and Tsung-Hsien Chang*, Ficus septica plant extracts for treating Dengue virus in vitro, PeerJ, 2017, 5, e3448.
11. Wan-Chi Tsai, Li-Yuan Bai, Yi-Jin Chen, Po-Chen Chu, Ya-Wen Hsu, Aaron M. Sargeant, and Jing-Ru Weng*, OSU-A9 Inhibits Pancreatic Cancer Cells by Modulating p38-JAK-STAT3 Signaling, Oncotarget, 2017, 8, 29233-29246.
12. Jing-Ru Weng*, Li-Yuan Bai, Wei-Yu Lin, Chang-Fang Chiu, Yu-Chang Chen, Shi-Wei Chao, and Chia-Hsien Feng, A flavone constituent from Myoporum bontioides induces M-phase cell cycle arrest of MCF-7 breast cancer cells, Molecules, 2017, 22, 472.
13. Chang-Fang Chiu, Jing-Ru Weng, Appaso Jadhav, Chia-Yung Wu, Aaron M. Sargeant , Li-Yuan Bai*, T315 T315 decreases acute myeloid leukemia cell viability through a combination of apoptosis induction and autophagic cell death,, International Journal of Molecular Sciences, 2016, 17, 1337-1350.
14. Chia-Hsien Wu, Li-Yuan Bai, Ming-Hsui Tsai, Po-Chen Chu, Chang-Fang Chiu, Michael Yuanchien Chen, Shih-Jiuan Chiu, Jo-Hua Chiang, and Jing-Ru Weng*, Pharmacological exploitation of the phenothiazine antipsychotics to develop novel antitumor agents – A drug repurposing strategy, Scientific Reports, 2016, 6, 27540-2750.
15. Li-Yuan Bai, Chang-Fang Chiu, Po-Chen Chu, Wei-Yu Lin, Shih-Jiuan Chiu, and Jing-Ru Weng*, A triterpenoid from wild bitter gourd inhibits breast cancer cells, Scientific Reports, 2016, 6, 22419-22428.
16. Li-Yuan Bai, Chang-Fang Chiu, Shih-Jiuan Chiu, Yu-Wen Chen, Jing-Lan Hu, Chia-Yung Wu, and Jing-Ru Weng*, Alphitolic acid, an anti-inflammatory triterpene, induces apoptosis and autophagy in oral squamous cell carcinoma cells, in part, through a p53-dependent pathway. Journal of Functional Foods, 2015, 18, 368-378.
17. Li-Yuan Bai, Chang-Fang Chiu, Naval P. Kapuriya, Tzong-Ming Shieh, Yu-Chen Tsai, Chia-Yung Wu, Aaron M. Sargeant, and Jing-Ru Weng*, BX795, a TBK1 inhibitor, exhibits antitumor activity in human oral squamous cell carcinoma through apoptosis induction and mitotic phase arrest. European Journal of Pharmacology, 2015, 769, 287-296.
18. Li-Yuan Bai, Chang-Fang Chiu, and Jing-Ru Weng*, Anti-tumor activities of triterpenes from Syzygium kusukusense. Natural Product Research, 2014, 9, 1557-1558.
19. Hany A. Omar, El-Shaimaa A. Arafa, Ibrahim A. Maghrabi, and Jing-Ru Weng*, Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a novel Akt/NF-kB signaling inhibitor. Basic & Clinical Pharmacology & Toxicology, 2014, 114, 464-471.
20. Chang-Fang Chiu, Li-Yuan Bai, Naval Kapuriya, Shih-Yuan Peng, Chia-Yung Wu, Aaron M. Sargeant, Michael Yuanchien Chen, and Jing-Ru Weng*Antitumor effects of BI-D1870 on human oral squamous cell carcinoma. Cancer Chemotherapy and Pharmacology. 2014, 347, 42-53.
21. Kai-Wei Lin, Zih-You Lin, A-Mei Huang, Jing-Ru Weng, Ming-Hong Yen, Shyh-Chyun Yang*, and Chun-Nan Lin, Lantabetulic acid derivatives induce G1 arrest and apoptosis in human prostate cancer cells. Archiv der Pharmazie Chemistry in Life Science, 2014, 347, 42-53.
22. Jing-Ru Weng*, I-Lu Lai, Hsiao-Ching Yang, Chun-Nan Lin, and Li-Yuan Bai, Identification of Kazinol Q, a Natural Product from Formosan plants, as an Inhibitor of DNA Methyltransferase. Phytotherapy Research, 2014, 28, 49-54.
23. Jing-Ru Weng*, Li-Yuan Bai, Chang-Fang Chiu, Jing-Lan Hu, Shih-Jiuan Chiu, and Chia-Yung Wu, Cucurbitane triterpenoid from Momordica charantia induces apoptosis and autophagy in breast cancer cells, in part, through peroxisome proliferator-activated receptor  activation. Evidence-Based Complementary and Alternative Medicine, 2013, Article ID 935675.




Click Num: